منابع مشابه
Microtubule Fine Structure
Recent studies have demonstrated the widespread occurrence of microtubules in the cytoplasm of both animal and plant cells (e.g., Burgos and Fawcett, 1955; Manton , 1959; Slautterback, 1963; Ledbetter and Porter, 1963). The microtubules have usually been examined in sectioned material after osmium tetroxide or glutaraldehyde fixation. Because of advantages in the negative staining technique, it...
متن کاملA "microtubule" in Plant Cell Fine Structure
This paper reports an electron microscope examination of the cortices of some plant cells engaged in wall formation. Previous studies of similar material fixed in OSO(4) alone have disclosed discontinuities in the plasma membrane and other evidence of inadequate fixation. After glutaraldehyde, used as a fixative in this present study, the general preservation of cortical fine structure is great...
متن کاملMicrotubule structure
Over the past year or so, there have been a number of advances regarding the structure and assembly of microtubules. Examples are kinesin-decorated microtubules (akin to decorated actomyosin), the direct visualization of GTP at microtubule ends, the expression of tubulins via chaperones, further effects of microtubule-associated proteins, drugs, and nucleotides on dynamic instability, and the b...
متن کاملNEW OBSERVATIONS ON FLAGELLAR FINE STRUCTURE The Relationship Between Matrix Structure and the Microtubule Component of the Axoneme
The sperm flagella of the blowfly Sarcophaga bullata demonstrate the relationship of radial projections in the matrix region to the microtubule organization of the axoneme . The A microtubule of each peripheral doublet is connected to the central sheath by a series of paired radial links . The links lie along the tubule wall with a alternate spacing of about 320/560 A. The distal end of each li...
متن کاملHow Taxol stabilises microtubule structure.
The structure of tubulin shows paclitaxel (Taxol(R)) binding to a pocket in beta tubulin on the microtubule's inner surface, which counteracts the effects of GTP hydrolysis occurring on the other side of the monomer.
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 1966
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.31.3.639